Motion Analyses in Modeling of Flow and Contaminant in Cleanrooms: A Review

Document Type : Review Article

Authors

1 Department of Mechanical Engineering, Faculty of Engineering, Razi University, Kermanshah, Iran

2 Department of Mechanical Engineering, Amirkabir University of Technology, Tehran, Iran

Abstract

The motion effect on the contaminant dispersion is a key parameter in cleanrooms. This parameter is ignored in many experimental and numerical studies because of its complexities but could cause errors in the obtained results. In real situations, particularly in isolating rooms and cleanrooms, the motion that is usually caused by the human moving and doors opening and closing leads to considerable flow changes that require attention. The present study aimed to explore studies that noticed and studied different aspects of the subject and to summarize the areas with priority for further investigation. Modeling the problem using experimental and numerical approaches requires steps and settings that are described in the experimental and numerical sections. The motion analysis is divided into two sections of human and door motions, covering the key findings of previous and recent publications, and concluding the required future studies. The results of approximately fifty published studies have revealed important findings related to cleanroom class degradation, temperature gradient reduction, increased contamination and secondary flow depth, and particle settlement in patients. These studies have shown that the ventilation system may need to be redesigned. Furthermore, it is crucial to consider the motion in both experimental and numerical studies based on the application. Additional research is necessary to further understand these findings.

Keywords

Main Subjects


[1]   N.P. Cheremisinoff, Handbook of air pollution prevention and control, Elsevier (2002).
[2]     B. Brunekreef, B. Forsberg, Epidemiological evidence of effects of coarse airborne particles on health, European respiratory journal, 26(2) (2005) 309-318.
[3]     C.A. Pope, D.W. Dockery, Health effects of fine particulate air pollution: lines that connect, Journal of the air & waste management association, 56(6) (2006) 709-742.
[4]     S.D. Adar, P.A. Filigrana, N. Clements, J.L. Peel, Ambient coarse particulate matter and human health: a systematic review and meta-analysis, Current environmental health reports, 1 (2014) 258-274.
[5]     C. Liu, J. Cai, R. Chen, F. Sera, Y. Guo, S. Tong, ... & H. Kan, Coarse particulate air pollution and daily mortality: a global study in 205 cities, American journal of respiratory and critical care medicine, 206(8) (2022) 999-1007.
[6]     P. Naughton, History of cleanrooms, ASHRAE Journal, 61(11) (2019) 38-54.
[7]     W. Whyte, Cleanroom technology: fundamentals of design, testing and operation, John Wiley & Sons (2010).
[8]     J.W. Useller, Clean room technology, Technology Utilization Division, National Aeronautics and Space Administration, (1969).
[9]     W.J. Whitfield, State of the art (contamination control) and laminar air-flow concept, Conference on Clean Room Specifications, Sandia Corporation, (1963) 73-84.
[10]   Z. Liu, M. Wu, H. Cao, Y. Wang, R. Rong, H. Zhu, Influence of the visitor walking on airflow and the bioaerosol particles in typical open tomb chambers: An experimental and case study, Buildings, 11(11) (2021) 538.
[11]   E.S. Mousavi, R. Jafarifiroozabadi, S. Bayramzadeh, A. Joseph, D. San, An observational study of door motion in operating rooms, Building and environment, 144 (2018) 502-507.
[12]   A. Bhattacharya, A.R. Metcalf, A.M. Nafchi, E.S. Mousavi, Particle dispersion in a cleanroom -effects of pressurization, door opening and traffic flow, Building Research & Information, 49(3) (2021a) 294-307.
[13]   S. Sadrizadeh, A. Aganovic, A. Bogdan, C. Wang, A. Afshari, A. Hartmann, ... & G. Cao, A systematic review of operating room ventilation, Journal of Building Engineering, 40 (2021) 102693.
[14]   X. Shao, K. Hashimoto, L. Fang, A.K. Melikov, K.G. Naydenov, C. Rasmuseen, Experimental study of airborne particle transmission through the doorway of a cleanroom due to the movement of a person, Building and environment, 183 (2020) 107205.
[15]   S.B. Poussou, S. Mazumdar, M.W. Plesniak, P.E. Sojka, Q. Chen, Flow and contaminant transport in an airliner cabin induced by a moving body: Model experiments and CFD predictions, Atmospheric Environment, 44(24) (2010) 2830-2839.
[16]   H. Zhou, K. Zhong, H. Jia, Y. Kang, Analysis of the effects of dynamic mesh update method on simulating indoor airflow induced by moving objects, Building and Environment, 212 (2022) 108782.
[17]   A. Kokkonen, M. Hyttinen, R. Holopainen, K. Salmi, P. Pasanen, Performance testing of engineering controls of airborne infection isolation rooms by tracer gas techniques, Indoor and Built Environment, 23(7) (2014) 994-1001.
[18]   P.E. Saarinen, P. Kalliomäki, J.W. Tang, H. Koskela, Large eddy simulation of air escape through a hospital isolation room single hinged doorway -validation by using tracer gases and simulated smoke videos, PloS one, 10(7) (2015) e0130667.
[19]   P. Saarinen, P. Kalliomäki, H. Koskela, J.W. Tang, Large-eddy simulation of the containment failure in isolation rooms with a sliding door -An experimental and modelling study, Building simulation, 11, (2018) 585-596.
[20]   L. Chang, X. Zhang, Y. Cai, Experimental determination of air inleakage to pressurized main control room caused by personnel entering, Building and Environment, 99 (2016b) 142-148.
[21]   L. Chang, S. Tu, W. Ye, X. Zhang, Dynamic simulation of contaminant inleakage produced by human walking into control room, International Journal of Heat and Mass Transfer, 113 (2017) 1179-1188.
[22]   W. Gao, X. Xie, Y. Liu, X. Chen, C. Zhu, Numerical simulation of the transport of breath-exhaled aerosol from manikin with realistic nasal airway over short social distances, Powder Technology, 437 (2024) 119543.
[23]   L. Chang, X. Zhang, S. Wang, J. Gao, Control room contaminant inleakage produced by door opening and closing: dynamic simulation and experiments, Building and environment, 98 (2016a) 11-20.
[24]   Y.C., Shih, C.C., Chiu, O. Wang, Dynamic airflow simulation within an isolation room, Building and environment, 42(9) (2007) 3194-3209.
[25]   P.L. Betts, I.H. Bokhari, Experiments on turbulent natural convection in an enclosed tall cavity, International Journal of Heat and Fluid Flow, 21(6) (2000) 675-683.
[26]   X. Yuan, Q. Chen, L.R. Glicksman, Measurements and computations of room airflow with displacement ventilation, ASHRAE Trans., 105 (1999) 340-352.
[27]   F. Chen, C.M. Simon, A.C. Lai, Modeling particle distribution and deposition in indoor environments with a new drift -flux model, Atmospheric Environment, 40(2) (2006) 357-367.
[28]   S.B. Poussou, Experimental investigation of airborne contaminant transport by a human wake moving in a ventilated aircraft cabin, Doctoral dissertation, Purdue University, (2008).
[29]   E. Bjorn, M. Mattsson, M. Sandberg, P.V. Nielsen, Displacement ventilation: effects of movement and exhalation, Dept. of Building Technology and Structural Engineering, Indoor Environmental Technology, 70 (1997).
[30]   S.J. Yang, W.S. Fu, A numerical investigation of effects of a moving operator on airflow patterns in a cleanroom, Building and environment, 37(7) (2002) 705-712.
[31]   H., Matsumoto, Y. Ohba, The influence of a moving object on air distribution in displacement ventilated rooms, Journal of Asian Architecture and Building Engineering, 3(1) (2004) 71-75.
[32]   H. Brohus, K.D. Balling, D. Jeppesen, Influence of movements on contaminant transport in an operating room, Indoor air, 16(5) (2006) 356-372.
[33]   T. Deng, Q. Zhang, G. Zhang, The influences of moving human in a ventilation room, Proceedings: Building Simulation, (2007) 779-786.
[34]   M. H. Saidi, B. Sajadi, G.R. Molaeimanesh, The effect of source motion on contaminant distribution in the cleanrooms, Energy and Buildings, 43(4) (2011) 966-970.
[35]   J. Wang, T.T. Chow, Numerical investigation of influence of human walking on dispersion and deposition of expiratory droplets in airborne infection isolation room, Building and Environment, 46(10) (2011) 1993-2002.   
[36]   T.T. Chow, J. Wang, Dynamic simulation on impact of surgeon bending movement on bacteria-carrying particles distribution in operating theatre, Building and environment, 57 (2012) 68-80.
[37]   Z. Han, W. Weng, Q. Huang, Numerical and experimental investigation on the dynamic airflow of human movement in a full-scale cabin, HVAC&R Research, 20(4) (2014) 444-457.
[38]   J. Hang, Y. Li, R. Jin, The influence of human walking on the flow and airborne transmission in a six-bed isolation room: Tracer gas simulation, Building and Environment, 77 (2014) 119-134.
[39]   Y. Wu, N. Gao, The dynamics of the body motion induced wake flow and its effects on the contaminant dispersion, Building and environment, 82 (2014) 63-74.
[40]   Y. Tao, K. Inthavong, J. Tu, Computational fluid dynamics study of human-induced wake and particle dispersion in indoor environment, Indoor and Built Environment, 26(2) (2017) 185-198.
[41]   S.J. Cao, D. Cen, W. Zhang, Z. Feng, Study on the impacts of human walking on indoor particles dispersion using momentum theory method, Building and Environment, 126 (2017) 195-206.
[42]   J., Eslami, A. Abbassi, M.H. Saidi, Numerical simulation of the effect of visitor's movement on bacteria-carrying particles distribution in hospital isolation room. Scientia Iranica, 24(3) (2017) 1160-1170.
[43]   Y. Tao, K. Inthavong, P. Petersen, K. Mohanarangam, W. Yang, J. Tu, Experimental visualisation of wake flows induced by different shaped moving manikins, Building and Environment, 142 (2018)  361-370.
[44]   N. Luo, W. Weng, X. Xu, M. Fu, Human-walking-induced wake flow–PIV experiments and CFD simulations, Indoor and Built Environment, 27(8) (2018) 1069-1084.
[45]   Z. Liu, H. Liu, R. Rong, G. Cao, Effect of a circulating nurse walking on airflow and bacteria-carrying particles in the operating room: An experimental and numerical study, Building and Environment, 186 (2020) 107315.
[46]   A. Bhattacharya, J. Pantelic, A. Ghahramani, E.S. Mousavi, Three‐dimensional analysis of the effect of human movement on indoor airflow patterns, Indoor Air, 31(2) (2021b) 587-601.
[47]   L. Feng, F. Zeng, R. Li, R. Ju, N. Gao, Influence of manikin movement on temperature stratification in a displacement ventilated room, Energy and Buildings, 234 (2021) 110700.
[48]   L. Lv, Y. Wu, C. Cao, L. Zeng, J. Gao, W. Xie, J. Zhang, Impact of different human walking patterns on flow and contaminant dispersion in residential kitchens: Dynamic simulation study, Building Simulation, Tsinghua University Press, (2022) 1-16.
[49]   M. Mahaki, M. Mattsson, M. Salmanzadeh, A. Hayati, Experimental and numerical simulations of human movement effect on the capture efficiency of a local exhaust ventilation system, Journal of Building Engineering, 52 (2022) 104444.
[50]   J. Wu, W. Weng, M. Fu, Y. Li, M. Lan, Enhancement effect of human movement on the high risk range of viral aerosols exhaled by a sitting person, Building and Environment, 218 (2022a) 109136.
[51]   J. Wu, W. Weng, M. Fu, Y. Li, Numerical study of transient indoor airflow and virus-laden droplet dispersion: Impact of interactive human movement, Science of The Total Environment, 869 (2023) 161750.
[52]   E. Belut, S. Lechene, B. Trouette, S. Vincent, G.H. Atallah, Flow and contaminant transfer at the interface of an aerodynamic containment barrier subjected to the wake of a moving obstacle. Building and Environment, 241 (2023) 110465.
[53]   H. Tan, K.Y. Wong, M.H.D. Othman, B.B. Nyakuma, D.D.C.V. Sheng, H.Y. Kek, ... & I.H. Hatif, Does human movement-induced airflow elevate infection risk in burn patient’s isolation ward? A validated dynamics numerical simulation approach, Energy and Buildings, 283 (2023) 112810.
[54]   F. Lu, X. Lingjun, C. Min, W. Yan, G. Naiping, Dynamic effects of occupant motion on indoor vertical thermal stratification in the displacement ventilation system, Energy and Buildings, 304 (2024) 113843.
[55]   S. Jo, G. Kim, M. Sung, A study on contaminant leakage from Airborne Infection Isolation room during medical staff entry; Implementation of walking motion on hypothetical human model in CFD simulation, Journal of Building Engineering, 86 (2024). 108812.
[56]   J. W. Tang, A. Nicolle, J. Pantelic, C.A. Klettner, R. Su, P. Kalliomaki, ... & K.W. Tham, Different types of door-opening motions as contributing factors to containment failures in hospital isolation rooms, PloS one, 8(6) (2013) e66663.
[57]   L. Fontana, A. Quintino, Experimental analysis of the transport of airborne contaminants between adjacent rooms at different pressure due to the door opening. Building and environment, 81 (2014) 81-91.
[58]   A. Hathway, I. Papakonstantis, A. Bruce-Konuah, W. Brevis, Experimental and modelling investigations of air exchange and infection transfer due to hinged-door motion in office and hospital settings, International Journal of Ventilation, 14(2) (2015) 127-140.
[59]   P. Kalliomäki, P. Saarinen, J.W. Tang, H. Koskela, Airflow patterns through single hinged and sliding doors in hospital isolation rooms, International Journal of Ventilation, 14(2) (2015) 111-126.
[60]   J. Hendiger, M. Chludzinska, P. Zietek, Influence of the pressure difference and door swing on heavy contaminants migration between rooms, PloS one, 11(5) (2016) e0155159.
[61]   P. Kalliomaki, P. Saarinen, J.W. Tang, H. Koskela, Airflow patterns through single hinged and sliding doors in hospital isolation rooms -Effect of ventilation, flow differential and passage, Building and Environment, 107 (2016) 154-168.
[62]   S. Lee, B. Park, T. Kurabuchi, Numerical evaluation of influence of door opening on interzonal air exchange. Building and environment, 102 (2016) 230-242.
[63]   E.S. Mousavi, K.R. Grosskopf, Airflow patterns due to door motion and pressurization in hospital isolation rooms, Science and Technology for the Built Environment, 22(4) (2016) 379-384.
[64]   J.M. Villafruela, J.F. San Jose, F. Castro, A. Zarzuelo, Airflow patterns through a sliding door during opening and foot traffic in operating rooms, Building and Environment, 109 (2016) 190-198.
[65]   I.G. Papakonstantis, E.A. Hathway, W. Brevis, An experimental study of the flow induced by the motion of a hinged door separating two rooms, Building and Environment, 131 (2018) 220-230.
[66]   S. Sadrizadeh, J. Pantelic, M. Sherman, J. Clark, O. Abouali, Airborne particle dispersion to an operating room environment during sliding and hinged door opening, Journal of infection and public health, 11(5) (2018) 631-635.
[67]   B. Zhou, L. Ding, F. Li, K. Xue, P.V. Nielsen, Y. Xu, Influence of opening and closing process of sliding door on interface airflow characteristic in operating room, Building and environment, 144 (2018) 459-473.
[68]   M.C. Lind, S. Sadrizadeh, B. Venas, P. Sadeghian, C. Wang, T.T. Harsem, Minimizing the airborne particle migration to the operating room during door opening, IOP Conference Series: Materials Science and Engineering, 609 (3) (2019) 032055.
[69]   C. Wang, S. Holmberg, S. Sadrizadeh, Impact of door opening on the risk of surgical site infections in an operating room with mixing ventilation, Indoor and Built Environment, 30(2) (2021) 166-179.
[70]   J.S.J. Alonso, M.A. Sanz-Tejedor, Y. Arroyo, M.R. San Jose-Gallego, Analysis and assessment of factors affecting air inflow from areas adjacent to operating rooms due to door opening and closing, Journal of Building Engineering, 49 (2022) 104109.
[71]   Y. Wu, L. Feng, M. Liu, Z. Wu, N. Gao, Numerical study on transient airflows and air exchange induced by door motion in thermally stratified environment, Building and Environment, 223 (2022b) 109498.
[72]   X. Shao, Y. Liu, Y. Hao, X. Wen, C. Li, X. Ma, ... & X. Li, Smoke visualization for the invasion of pollutants during door-opening process in pharmaceutical cleanrooms: Effects of initial pressure differential and airlock barriers, Energy and Buildings, 279 (2023) 112711.
[73]   M. Zheng, Y. Fan, X. Li, D. Lester, X. Chen, Y. Li, I. Cole, Aerosol exchange between pressure-equilibrium rooms induced by door motion and human movement, Building and Environment, 241 (2023) 110486.