Prediction of Flow Behavior and Level of Hemolysis in a Pulsatile LVAD

Document Type : Research Article

Authors

University of Guilan

Abstract

Heart failure claims the lives of thousands people annually. Left ventricular assist device (LVAD) is a valid treatment option for patients with advanced stage of HF. The LVAD is a blood pump increasing the pumping ability of the bottom left chamber of patient's heart. In this study, we investigate the hemolytic characteristics of a LVAD. The main objective of this paper is to explore the effects of amplitude and frequency on levels of hemolysis via computational fluid dynamic (CFD) in an implantable reciprocating pump. Thus, dynamic mesh technique is utilized in order to simulate piston motion and valves closure. Moreover, a system of time-dependent nonlinear partial differential equations is coupled with each other to predict blood flow and hemolysis index. Fluid dynamic characteristics are obtained by employing continuity and momentum equations and the levels of hemolysis are also calculated by applying two additional scalar transport equations based on an Eulerian transport approach. The results depicted the favorable reduction in hemolysis index by increasing frequency and decreasing amplitude simultaneously at specific Reynolds number, they also showed that the average hemolysis (Havg) at right side of piston is slightly higher than left side and it obtains its maximum value at valves and clearance domains.

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