Amirkabir University of TechnologyAUT Journal of Mechanical Engineering2588-29375320210901Numerical investigation of cardiac function parameters in left heart hemodynamics with stenosed mitral465476417710.22060/ajme.2020.18606.5906ENMaysamSaidiMechanical Engineering Department, Razi University, Kermanshah, Iran0000-0001-7423-334XRezaSamianEnergy Research Center, Amirkabir University of Technology, Tehran, IranJournal Article20200616This work studies the effect of cardiac function parameters on ventricular flow pattern in a stenosed mitral.A three-dimensional simulation is performed employing dynamic mesh based on a geometry and valve flow rates extracted from medical images. Different mitral areas from 6 to 2 cm<sup>2</sup> then different parameters for stenosed 2 cm<sup>2</sup> case are investigated. Special attention has been drawn to compare wall shear stress, blood velocity and pressure distribution, while the power used by ventricle and atrium to pump the blood are also highlighted. Computing the power used by the heart walls to move the blood shows that the stenosed mitral increases the needed force and the energy for the blood flow suction during the early diastole (from 0.06 W for mitral area of 6 cm<sup>2</sup> to 1.28 W for mitral area of 2 cm<sup>2</sup>). For the stenosed mitral area of 2 cm<sup>2</sup>, in the systole, decreasing the ejection fraction to half decreased the maximum ventricle power to around half. In the diastole, decreasing the E/A which is the ratio of early diastole (E wave) and late diastole (A wave) ratio from 4.8 to 1 decreased the maximum ventricle power to one-third. The numerical results confirmed that the compensation mechanism to afford the pumping power could be changing the E/A ratio which leads to enlarged atrium.https://ajme.aut.ac.ir/article_4177_faa6b6acb742a940ccd8d0a327fb1b58.pdf